Pralidoxime + Atropine Interaction

Moderateinteraction on record

Description

Pralidoxime may potentiate atropine effect, causing earlier onset of atropinization signs (flushing, mydriasis, tachycardia, dryness of mouth/nose). Excitement and manic behavior post-consciousness recovery reported.

Mechanism

Pralidoxime potentiates the effect of atropine

Source: NLP:atropine