Selpercatinib + P Gp Or Bcrp Substrates Interaction
Moderateinteraction on record
Description
RETEVMO is a P-gp inhibitor; concomitant use increases substrate plasma concentrations. Avoid coadministration; if unavoidable, modify substrate dosage per product labeling.
Mechanism
P-gp inhibition increases substrate concentrations
Source: NLP:selpercatinib