Short Acting Antacids + Avutometinib Potassium And Defactinib Hydrochloride Interaction

Moderateinteraction on record

Description

If use cannot be avoided, administer FAKZYNJA 2 hours before or 2 hours after the antacid to minimize exposure reduction.

Mechanism

Gastric acid reduction decreases defactinib exposure

Source: NLP:avutometinib potassium and defactinib hydrochloride