Somatrogon Ghla + Prednisone Interaction
Moderateinteraction on record
Description
NGENLA may inhibit 11βHSD-1 and reduce serum cortisol concentrations. Patients on prednisone replacement for hypoadrenalism may require increased maintenance or stress doses.
Mechanism
Growth hormone inhibits 11β-hydroxysteroid dehydrogenase type 1, reducing conversion of prednisone to active metabolite
Source: NLP:somatrogon-ghla