Strong Cyp3a4 And P Glycoprotein Inducers + Everolimus Interaction

Contraindicatedinteraction on record

Description

Avoid concomitant use of P-gp and strong CYP3A4 inhibitors with everolimus due to increased drug exposure.

Mechanism

Inhibition of P-glycoprotein and CYP3A4 metabolism

Source: NLP:everolimus