Does Succinylcholine Interact with Metoclopramide Hydrochloride?
Succinylcholine and Metoclopramide Hydrochloride have a unknown drug interaction according to U.S. FDA drug labeling data. Metoclopramide inhibits plasma cholinesterase; interaction mentioned but severity not fully specified in text. The mechanism involves plasma cholinesterase inhibition. Patients taking both medications should consult their healthcare provider before starting, stopping, or changing the dosage of either drug. This information is based on official FDA drug labeling sourced from OpenFDA and the NIH National Library of Medicine.
- Severity
- Unknown
- Management
- Consult your pharmacist
- Data Source
- U.S. FDA via OpenFDA
How This Interaction Works
The interaction between Succinylcholine and Metoclopramide Hydrochloride occurs because plasma cholinesterase inhibition. Clinically, this means metoclopramide inhibits plasma cholinesterase; interaction mentioned but severity not fully specified in text.
What To Tell Your Doctor or Pharmacist
If you are taking Succinylcholine and your doctor is considering prescribing Metoclopramide Hydrochloride (or vice versa), make sure to:
- Inform your doctor and pharmacist of all current medications, including over-the-counter drugs and supplements
- Ask whether the benefits of combining these medications outweigh the risks for your specific situation
- Ask what symptoms to watch for that would indicate the interaction is causing problems
- Never stop or change either medication without first consulting your healthcare provider