Does Sucralfate Interact with Furosemide Benzalkonium Chloride?
Sucralfate and Furosemide Benzalkonium Chloride have a moderate drug interaction according to U.S. FDA drug labeling data. Simultaneous administration of sucralfate and furosemide tablets may reduce the natriuretic and antihypertensive effects of furosemide. Doses should be separated by at least two hours. The mechanism involves reduced absorption/effect of furosemide. Patients taking both medications should consult their healthcare provider before starting, stopping, or changing the dosage of either drug. This information is based on official FDA drug labeling sourced from OpenFDA and the NIH National Library of Medicine.
- Severity
- Moderate
- Sucralfate Class
- Aluminum Complex
- Management
- Monitor for effects
- Data Source
- U.S. FDA via OpenFDA
How This Interaction Works
The interaction between Sucralfate and Furosemide Benzalkonium Chloride occurs because reduced absorption/effect of furosemide. Clinically, this means simultaneous administration of sucralfate and furosemide tablets may reduce the natriuretic and antihypertensive effects of furosemide. doses should be separated by at least two hours. This is classified as a moderate interaction. While it may not require stopping either medication, your healthcare provider should be aware you are taking both so they can monitor for potential effects and adjust treatment if necessary.
What To Tell Your Doctor or Pharmacist
If you are taking Sucralfate and your doctor is considering prescribing Furosemide Benzalkonium Chloride (or vice versa), make sure to:
- Inform your doctor and pharmacist of all current medications, including over-the-counter drugs and supplements
- Ask whether the benefits of combining these medications outweigh the risks for your specific situation
- Ask what symptoms to watch for that would indicate the interaction is causing problems
- Ask whether any dosage adjustments are needed
- Never stop or change either medication without first consulting your healthcare provider