Does Tecovirimat Monohydrate Interact with Omeprazole?
Tecovirimat Monohydrate and Omeprazole have a unknown drug interaction according to U.S. FDA drug labeling data. 7.3 Drugs Without Clinically Significant Interactions With TPOXX Based on a drug interaction study, no clinically significant drug interactions have been observed when TPOXX is co-administered with bupropion, flurbiprofen, or omeprazole [see Clinical Pharmacology ( 12.3 )] . Patients taking both medications should consult their healthcare provider before starting, stopping, or changing the dosage of either drug. This information is based on official FDA drug labeling sourced from OpenFDA and the NIH National Library of Medicine.
- Severity
- Unknown
- Tecovirimat Monohydrate Class
- Orthopoxvirus VP37 Envelope Wrapping Protein Inhibitor
- Omeprazole Class
- Proton Pump Inhibitor
- Management
- Consult your pharmacist
- Data Source
- U.S. FDA via OpenFDA
What To Tell Your Doctor or Pharmacist
If you are taking Tecovirimat Monohydrate and your doctor is considering prescribing Omeprazole (or vice versa), make sure to:
- Inform your doctor and pharmacist of all current medications, including over-the-counter drugs and supplements
- Ask whether the benefits of combining these medications outweigh the risks for your specific situation
- Ask what symptoms to watch for that would indicate the interaction is causing problems
- Never stop or change either medication without first consulting your healthcare provider