Does Thioridazine Interact with Pindolol?
CDI records a moderate classification for Thioridazine and Pindolol. The stored summary is: Pindolol increases serum thioridazine levels; pindolol levels may also be increased with coadministration. Monitor therapy. The mechanism involves mutual pharmacokinetic interaction. Patients taking both medications should consult their healthcare provider before starting, stopping, or changing the dosage of either drug. This record was extracted from drug labeling through openFDA. NIH/NLM RxNorm is used for drug identities. The summary and severity classification are CDI's processed information, not a verbatim source quotation. Product, route, and patient circumstances matter.
- Severity
- Moderate
- Pindolol Class
- beta-Adrenergic Blocker
- Management
- Monitor for effects
- Data Source
- U.S. FDA via OpenFDA
Recorded Mechanism
Mutual pharmacokinetic interaction
What To Tell Your Doctor or Pharmacist
If you are taking Thioridazine and your doctor is considering prescribing Pindolol (or vice versa), make sure to:
- Inform your doctor and pharmacist of all current medications, including over-the-counter drugs and supplements
- Ask whether the benefits of combining these medications outweigh the risks for your specific situation
- Ask what symptoms to watch for that would indicate the interaction is causing problems
- Ask whether any dosage adjustments are needed
- Never stop or change either medication without first consulting your healthcare provider