Does Triamterene Interact with Captopril And Hydrochlorothiazide?
CDI records a major classification for Triamterene and Captopril And Hydrochlorothiazide. The stored summary is: May cause significant increase in serum potassium. Should only be given for documented hypokalemia and with caution due to risk of hyperkalemia. The mechanism involves captopril decreases aldosterone production; triamterene is potassium-sparing. Patients taking both medications should consult their healthcare provider before starting, stopping, or changing the dosage of either drug. This record was extracted from drug labeling through openFDA. NIH/NLM RxNorm is used for drug identities. The summary and severity classification are CDI's processed information, not a verbatim source quotation. Product, route, and patient circumstances matter.
- Severity
- Major
- Triamterene Class
- Potassium-sparing Diuretic
- Captopril And Hydrochlorothiazide Class
- Thiazide Diuretic
- Management
- Close medical supervision required
- Data Source
- U.S. FDA via OpenFDA
Recorded Mechanism
Captopril decreases aldosterone production; triamterene is potassium-sparing
What To Tell Your Doctor or Pharmacist
If you are taking Triamterene and your doctor is considering prescribing Captopril And Hydrochlorothiazide (or vice versa), make sure to:
- Inform your doctor and pharmacist of all current medications, including over-the-counter drugs and supplements
- Ask whether the benefits of combining these medications outweigh the risks for your specific situation
- Ask what symptoms to watch for that would indicate the interaction is causing problems
- Ask how frequently you should be monitored while these are co-prescribed
- Ask whether any dosage adjustments are needed
- Never stop or change either medication without first consulting your healthcare provider