Does Ustekinumab Auub Interact with Androgen Deprivation Therapeutic Drugs?
Ustekinumab Auub and Androgen Deprivation Therapeutic Drugs have a moderate drug interaction according to U.S. FDA drug labeling data. Ustekinumab may normalize CYP450 enzyme formation upon initiation or discontinuation; monitor therapeutic effect and adjust dosage as needed. The mechanism involves ustekinumab antagonizes il-12/il-23, potentially normalizing cyp450 enzyme suppression caused by chronic inflammation. Patients taking both medications should consult their healthcare provider before starting, stopping, or changing the dosage of either drug. This information is based on official FDA drug labeling sourced from OpenFDA and the NIH National Library of Medicine.
- Severity
- Moderate
- Ustekinumab Auub Class
- Interleukin-12 Antagonist
- Management
- Monitor for effects
- Data Source
- U.S. FDA via OpenFDA
How This Interaction Works
The interaction between Ustekinumab Auub and Androgen Deprivation Therapeutic Drugs occurs because ustekinumab antagonizes il-12/il-23, potentially normalizing cyp450 enzyme suppression caused by chronic inflammation. Clinically, this means ustekinumab may normalize cyp450 enzyme formation upon initiation or discontinuation; monitor therapeutic effect and adjust dosage as needed. This is classified as a moderate interaction. While it may not require stopping either medication, your healthcare provider should be aware you are taking both so they can monitor for potential effects and adjust treatment if necessary.
What To Tell Your Doctor or Pharmacist
If you are taking Ustekinumab Auub and your doctor is considering prescribing Androgen Deprivation Therapeutic Drugs (or vice versa), make sure to:
- Inform your doctor and pharmacist of all current medications, including over-the-counter drugs and supplements
- Ask whether the benefits of combining these medications outweigh the risks for your specific situation
- Ask what symptoms to watch for that would indicate the interaction is causing problems
- Ask whether any dosage adjustments are needed
- Never stop or change either medication without first consulting your healthcare provider