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Does Viloxazine Hydrochloride Interact with Monoamine Oxidase Inhibitors Maois?

Viloxazine Hydrochloride and Monoamine Oxidase Inhibitors Maois have a contraindicated drug interaction according to U.S. FDA drug labeling data. Concomitant use may lead to potentially life-threatening hypertensive crisis. Concomitant use or use within 2 weeks after discontinuing an MAOI is contraindicated. Patients taking both medications should consult their healthcare provider before starting, stopping, or changing the dosage of either drug. This information is based on official FDA drug labeling sourced from OpenFDA and the NIH National Library of Medicine.

Severity
Contraindicated
Management
Do not take together
Data Source
U.S. FDA via OpenFDA

What To Tell Your Doctor or Pharmacist

If you are taking Viloxazine Hydrochloride and your doctor is considering prescribing Monoamine Oxidase Inhibitors Maois (or vice versa), make sure to:

  • Inform your doctor and pharmacist of all current medications, including over-the-counter drugs and supplements
  • Ask whether the benefits of combining these medications outweigh the risks for your specific situation
  • Ask what symptoms to watch for that would indicate the interaction is causing problems
  • Ask about alternative medications that do not interact with your current regimen
  • Ask how frequently you should be monitored while these are co-prescribed
  • Never stop or change either medication without first consulting your healthcare provider
💊 Viloxazine Hydrochloride(Qelbree)+💊 Monoamine Oxidase Inhibitors Maois

Severity & Interaction Details

⛔
contraindicated
Avoid this combination
FDA labeling lists this pair as contraindicated. The risk outweighs the benefit in nearly all cases.
Severity scale
MinorContra
On record
Yes
Drug A class
—
Drug B class
—
Source
NLP:viloxazine hydrochloride

What this means in plain English

Concomitant use may lead to potentially life-threatening hypertensive crisis. Concomitant use or use within 2 weeks after discontinuing an MAOI is contraindicated.

About Viloxazine Hydrochloride and Monoamine Oxidase Inhibitors Maois

Viloxazine Hydrochloride is also sold under the brand name Qelbree. Viloxazine Hydrochloride is taken by mouth. Viloxazine Hydrochloride additionally carries an FDA boxed warning, the FDA's strongest safety alert.

Recent research & FDA safety updates

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Auto-aggregated from PubMed E-utilities and FDA safety data.

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Data integrity: Every interaction shown is extracted directly from official U.S. FDA drug labeling via openFDA and the U.S. National Library of Medicine (NIH) — no interactions are invented, inferred, or manually edited. Maintained by CheckDrugInteractions.com. See our methodology or report a correction at support@checkdruginteractions.com.

Data sourced from U.S. FDA drug labeling via openFDA and the NIH National Library of Medicine, supplemented with a small number of well-established interactions from curated clinical references. For informational purposes only. Always consult your pharmacist or physician.