Home›Abacavir Sulfate Dolutegravir Sodium Lamivudine›Abacavir Sulfate Dolutegravir Sodium Lamivudine + Midazolam

Does Abacavir Sulfate Dolutegravir Sodium Lamivudine Interact with Midazolam?

CDI records a unknown classification for Abacavir Sulfate Dolutegravir Sodium Lamivudine and Midazolam. The stored summary is: In drug interaction trials, dolutegravir did not have a clinically relevant effect on the pharmacokinetics of the following drugs: tenofovir, methadone, midazolam, rilpivirine, and oral contraceptives containing norgestimate and ethinyl estradiol. Patients taking both medications should consult their healthcare provider before starting, stopping, or changing the dosage of either drug. This record was extracted from drug labeling through openFDA. NIH/NLM RxNorm is used for drug identities. The summary and severity classification are CDI's processed information, not a verbatim source quotation. Product, route, and patient circumstances matter.

Evidence status

A current label comparison is not yet available for this record. The summary and severity are stored CDI information; they have not been independently validated on this page against the exact product label.

Confirm the medicine, formulation, route, and applicable warning with your pharmacist or prescriber. Independent clinical review has not been recorded.

Stored CDI classification: Unknown
Abacavir Sulfate Dolutegravir Sodium Lamivudine Class: Hepatitis B Virus Nucleoside Analog Reverse Transcriptase Inhibitor
Midazolam Class: Benzodiazepine
Management: Confirm exact products with your pharmacist
Data Source: U.S. FDA via OpenFDA

What To Tell Your Doctor or Pharmacist

If you are taking Abacavir Sulfate Dolutegravir Sodium Lamivudine and your doctor is considering prescribing Midazolam (or vice versa), make sure to:

Inform your doctor and pharmacist of all current medications, including over-the-counter drugs and supplements
Ask whether the benefits of combining these medications outweigh the risks for your specific situation
Ask what symptoms to watch for that would indicate the interaction is causing problems
Never stop or change either medication without first consulting your healthcare provider

💊 Abacavir Sulfate Dolutegravir Sodium Lamivudine(Triumeq)+💊 Midazolam(Nayzilam)

Severity & Interaction Details

ℹ️

unknown

Stored CDI classification: unknown

A current source comparison has not been recorded for this claim. The stored classification does not determine the clinical significance for your exact products or circumstances.

Severity scale

MinorContra

On record

Yes

Drug A class

Hepatitis B Virus Nucleoside Analog Reverse Transcriptase Inhibitor

Drug B class

Benzodiazepine

Source

FDA drug label - abacavir sulfate, dolutegravir sodium, lamivudine

What this means in plain English

In drug interaction trials, dolutegravir did not have a clinically relevant effect on the pharmacokinetics of the following drugs: tenofovir, methadone, midazolam, rilpivirine, and oral contraceptives containing norgestimate and ethinyl estradiol.

About Abacavir Sulfate Dolutegravir Sodium Lamivudine and Midazolam

Abacavir Sulfate Dolutegravir Sodium Lamivudine is a Hepatitis B Virus Nucleoside Analog Reverse Transcriptase Inhibitor, while Midazolam is a Benzodiazepine. You may recognize them by the brand names Triumeq and Nayzilam. Both Abacavir Sulfate Dolutegravir Sodium Lamivudine and Midazolam carry an FDA boxed warning — the agency's most serious safety designation.

Source and Limitations

This record was produced by automated extraction from drug-label information, including AI processing. The summary and mechanism are not verbatim FDA quotations. The drug profiles below may describe different formulations from the source label. Confirm the exact product and route with your pharmacist. This page does not establish independent clinical review.

📖 Source: FDA drug label - abacavir sulfate, dolutegravir sodium, lamivudine

Recent research & FDA safety updates

Live

Auto-aggregated from PubMed E-utilities and FDA safety data.

PubMed

ARMED: an Australian cohort retrospective observational study to understand motivations for switching and clinical outcomes of individuals switching to dolutegravir/lamivudine.about Abacavir Sulfate Dolutegravir Sodium Lamivudine · 2026-10

PubMed

Bilateral Pathological Femoral Fractures Secondary to Long-Term Tenofovir Disoproxil Fumarate-Induced Osteomalacia in a Woman Living with HIV: A Case Report.about Abacavir Sulfate Dolutegravir Sodium Lamivudine · 2026-08

PubMed

Pharmacokinetics of abacavir and lamivudine in infants living with HIV with and without rifampicin co-treatment.about Abacavir Sulfate Dolutegravir Sodium Lamivudine · 2026-08

Share this result:

WhatsApp Text / SMS Email

Also share on:X Facebook

Add more drugs

Check Abacavir Sulfate Dolutegravir Sodium Lamivudine and Midazolam against your full medication list

Most patients take more than two medications. CDI checks every pair across up to 20 drugs simultaneously — including OTCs and common supplements.

Add more drugs →

How this information is prepared: CDI uses automated extraction, including AI, to summarize drug labeling from openFDA and includes separately identified curated-reference records. RxNorm helps identify medications; it does not verify interaction claims. Extracted summaries and CDI severity classifications can contain errors and are not verbatim FDA statements or independent clinical review. Maintained by CheckDrugInteractions.com. See our methodology or report a correction at support@checkdruginteractions.com.

Data sourced from U.S. FDA drug labeling via openFDA and the NIH National Library of Medicine, supplemented with a small number of well-established interactions from curated clinical references. For informational purposes only. Always consult your pharmacist or physician.