Home›Acetaminophen›Acetaminophen + Rimantadine Hydrochloride

Does Acetaminophen Interact with Rimantadine Hydrochloride?

Acetaminophen and Rimantadine Hydrochloride have a minor drug interaction according to U.S. FDA drug labeling data. Co-administration reduced peak concentration and AUC values for rimantadine by approximately 11%. Patients taking both medications should consult their healthcare provider before starting, stopping, or changing the dosage of either drug. This information is based on official FDA drug labeling sourced from OpenFDA and the NIH National Library of Medicine.

Severity: Minor
Management: Generally manageable
Data Source: U.S. FDA via OpenFDA

What To Tell Your Doctor or Pharmacist

If you are taking Acetaminophen and your doctor is considering prescribing Rimantadine Hydrochloride (or vice versa), make sure to:

Inform your doctor and pharmacist of all current medications, including over-the-counter drugs and supplements
Ask whether the benefits of combining these medications outweigh the risks for your specific situation
Ask what symptoms to watch for that would indicate the interaction is causing problems
Never stop or change either medication without first consulting your healthcare provider

💊 Acetaminophen(Little Fevers)+💊 Rimantadine Hydrochloride(Flumadine)

Severity & Interaction Details

✅

minor

Generally safe — minor interaction

Low clinical significance. Routine awareness is usually sufficient.

Severity scale

MinorContra

On record

Yes

Drug A class

—

Drug B class

—

Source

NLP:rimantadine hydrochloride

What this means in plain English

Co-administration reduced peak concentration and AUC values for rimantadine by approximately 11%.

About Acetaminophen and Rimantadine Hydrochloride

You may recognize them by the brand names Little Fevers and Flumadine. Acetaminophen is given by intravenous (IV) infusion, whereas Rimantadine Hydrochloride is taken by mouth. Acetaminophen additionally carries an FDA boxed warning, the FDA's strongest safety alert.

Share this result:

WhatsApp Text / SMS Email

Also share on:X Facebook

Add more drugs

Check Acetaminophen and Rimantadine Hydrochloride against your full medication list

Most patients take more than two medications. CDI checks every pair across up to 20 drugs simultaneously — including OTCs and common supplements.

Add more drugs →

Data integrity: Every interaction shown is extracted directly from official U.S. FDA drug labeling via openFDA and the U.S. National Library of Medicine (NIH) — no interactions are invented, inferred, or manually edited. Maintained by CheckDrugInteractions.com. See our methodology or report a correction at support@checkdruginteractions.com.

Data sourced from U.S. FDA drug labeling via openFDA and the NIH National Library of Medicine, supplemented with a small number of well-established interactions from curated clinical references. For informational purposes only. Always consult your pharmacist or physician.