Acetylsalicylic Acid + Methylprednisolone Interaction
Moderateinteraction on record
Description
Methylprednisolone may increase the clearance of chronic high dose aspirin, leading to decreased salicylate levels or increased toxicity upon withdrawal. Use cautiously in hypoprothrombinemia patients.
Mechanism
Increased clearance of aspirin
Source: NLP:methylprednisolone