Does Adrenergic Blockers Interact with Dextroamphetamine Saccharate Amphetamine Aspartate Monohydra?
Adrenergic Blockers and Dextroamphetamine Saccharate Amphetamine Aspartate Monohydra have a moderate drug interaction according to U.S. FDA drug labeling data. Adrenergic blockers are inhibited by amphetamines, potentially reducing their therapeutic effect. The mechanism involves amphetamines inhibit adrenergic blockers. Patients taking both medications should consult their healthcare provider before starting, stopping, or changing the dosage of either drug. This information is based on official FDA drug labeling sourced from OpenFDA and the NIH National Library of Medicine.
- Severity
- Moderate
- Management
- Monitor for effects
- Data Source
- U.S. FDA via OpenFDA
How This Interaction Works
The interaction between Adrenergic Blockers and Dextroamphetamine Saccharate Amphetamine Aspartate Monohydra occurs because amphetamines inhibit adrenergic blockers. Clinically, this means adrenergic blockers are inhibited by amphetamines, potentially reducing their therapeutic effect. This is classified as a moderate interaction. While it may not require stopping either medication, your healthcare provider should be aware you are taking both so they can monitor for potential effects and adjust treatment if necessary.
What To Tell Your Doctor or Pharmacist
If you are taking Adrenergic Blockers and your doctor is considering prescribing Dextroamphetamine Saccharate Amphetamine Aspartate Monohydra (or vice versa), make sure to:
- Inform your doctor and pharmacist of all current medications, including over-the-counter drugs and supplements
- Ask whether the benefits of combining these medications outweigh the risks for your specific situation
- Ask what symptoms to watch for that would indicate the interaction is causing problems
- Ask whether any dosage adjustments are needed
- Never stop or change either medication without first consulting your healthcare provider