Does Azelastine Hydrochloride Fluticasone Propionate Interact with Alcohol?
Azelastine Hydrochloride Fluticasone Propionate and Alcohol have a major drug interaction according to U.S. FDA drug labeling data. Central nervous system depressant; concurrent use should be avoided due to risk of somnolence and impairment of CNS performance. The mechanism involves cns depression. Patients taking both medications should consult their healthcare provider before starting, stopping, or changing the dosage of either drug. This information is based on official FDA drug labeling sourced from OpenFDA and the NIH National Library of Medicine.
- Severity
- Major
- Management
- Close medical supervision required
- Data Source
- U.S. FDA via OpenFDA
How This Interaction Works
The interaction between Azelastine Hydrochloride Fluticasone Propionate and Alcohol occurs because cns depression. Clinically, this means central nervous system depressant; concurrent use should be avoided due to risk of somnolence and impairment of cns performance. This is classified as a major interaction, meaning it could cause serious harm if not properly managed. Your healthcare provider may need to adjust dosages, substitute one medication, or increase monitoring frequency.
What To Tell Your Doctor or Pharmacist
If you are taking Azelastine Hydrochloride Fluticasone Propionate and your doctor is considering prescribing Alcohol (or vice versa), make sure to:
- Inform your doctor and pharmacist of all current medications, including over-the-counter drugs and supplements
- Ask whether the benefits of combining these medications outweigh the risks for your specific situation
- Ask what symptoms to watch for that would indicate the interaction is causing problems
- Ask how frequently you should be monitored while these are co-prescribed
- Ask whether any dosage adjustments are needed
- Never stop or change either medication without first consulting your healthcare provider