Home›Bisoprolol Fumarate And Hydrochlorothiazide›Bisoprolol Fumarate And Hydrochlorothiazide + Digitalis Glycosides

Does Bisoprolol Fumarate And Hydrochlorothiazide Interact with Digitalis Glycosides?

Bisoprolol Fumarate And Hydrochlorothiazide and Digitalis Glycosides have a major drug interaction according to U.S. FDA drug labeling data. Both digitalis and beta-blockers slow AV conduction and decrease heart rate. Concomitant use increases risk of bradycardia. The mechanism involves additive effects on av conduction and heart rate. Patients taking both medications should consult their healthcare provider before starting, stopping, or changing the dosage of either drug. This information is based on official FDA drug labeling sourced from OpenFDA and the NIH National Library of Medicine.

Severity
Major
Bisoprolol Fumarate And Hydrochlorothiazide Class
Thiazide Diuretic
Management
Close medical supervision required
Data Source
U.S. FDA via OpenFDA

How This Interaction Works

The interaction between Bisoprolol Fumarate And Hydrochlorothiazide and Digitalis Glycosides occurs because additive effects on av conduction and heart rate. Clinically, this means both digitalis and beta-blockers slow av conduction and decrease heart rate. concomitant use increases risk of bradycardia. This is classified as a major interaction, meaning it could cause serious harm if not properly managed. Your healthcare provider may need to adjust dosages, substitute one medication, or increase monitoring frequency.

What To Tell Your Doctor or Pharmacist

If you are taking Bisoprolol Fumarate And Hydrochlorothiazide and your doctor is considering prescribing Digitalis Glycosides (or vice versa), make sure to:

  • Inform your doctor and pharmacist of all current medications, including over-the-counter drugs and supplements
  • Ask whether the benefits of combining these medications outweigh the risks for your specific situation
  • Ask what symptoms to watch for that would indicate the interaction is causing problems
  • Ask how frequently you should be monitored while these are co-prescribed
  • Ask whether any dosage adjustments are needed
  • Never stop or change either medication without first consulting your healthcare provider
💊 Bisoprolol Fumarate And Hydrochlorothiazide(Bisoprolol Fumarate And Hydrochlorothiazide)+💊 Digitalis Glycosides

Severity & Interaction Details

⚠️
major
Use with caution — major interaction
Serious risk of clinically significant harm. Generally avoid; if used, monitor closely.
Severity scale
MinorContra
On record
Yes
Drug A class
Thiazide Diuretic
Drug B class
—
Source
NLP:bisoprolol fumarate and hydrochlorothiazide

What this means in plain English

Both digitalis and beta-blockers slow AV conduction and decrease heart rate. Concomitant use increases risk of bradycardia.

What the FDA label says

"Additive effects on AV conduction and heart rate"

📖 Source: NLP:bisoprolol fumarate and hydrochlorothiazide

Share this result:XFacebookWhatsAppReddit
Add more drugs
Check Bisoprolol Fumarate And Hydrochlorothiazide and Digitalis Glycosides against your full medication list

Most patients take more than two medications. CDI checks every pair across up to 20 drugs simultaneously — including OTCs and common supplements.

Add more drugs →

Data sourced from U.S. FDA drug labeling via openFDA and the NIH National Library of Medicine. For informational purposes only. Always consult your pharmacist or physician.