Does Bisoprolol Fumarate And Hydrochlorothiazide Interact with Diltiazem?
Bisoprolol Fumarate And Hydrochlorothiazide and Diltiazem have a moderate drug interaction according to U.S. FDA drug labeling data. Calcium antagonist that may depress myocardium and inhibit AV conduction. Use with caution when combined with bisoprolol. The mechanism involves additive myocardial depression and av conduction inhibition. Patients taking both medications should consult their healthcare provider before starting, stopping, or changing the dosage of either drug. This information is based on official FDA drug labeling sourced from OpenFDA and the NIH National Library of Medicine.
- Severity
- Moderate
- Bisoprolol Fumarate And Hydrochlorothiazide Class
- Thiazide Diuretic
- Management
- Monitor for effects
- Data Source
- U.S. FDA via OpenFDA
How This Interaction Works
The interaction between Bisoprolol Fumarate And Hydrochlorothiazide and Diltiazem occurs because additive myocardial depression and av conduction inhibition. Clinically, this means calcium antagonist that may depress myocardium and inhibit av conduction. use with caution when combined with bisoprolol. This is classified as a moderate interaction. While it may not require stopping either medication, your healthcare provider should be aware you are taking both so they can monitor for potential effects and adjust treatment if necessary.
What To Tell Your Doctor or Pharmacist
If you are taking Bisoprolol Fumarate And Hydrochlorothiazide and your doctor is considering prescribing Diltiazem (or vice versa), make sure to:
- Inform your doctor and pharmacist of all current medications, including over-the-counter drugs and supplements
- Ask whether the benefits of combining these medications outweigh the risks for your specific situation
- Ask what symptoms to watch for that would indicate the interaction is causing problems
- Ask whether any dosage adjustments are needed
- Never stop or change either medication without first consulting your healthcare provider