Does Carbidopa Interact with Carbidopa Levodopa And Entacapone?
CDI records a major classification for Carbidopa and Carbidopa Levodopa And Entacapone. The stored summary is: May result in increased heart rates, possibly arrhythmias, and excessive changes in blood pressure. Metabolized by COMT. The mechanism involves comt metabolism inhibition by entacapone. Patients taking both medications should consult their healthcare provider before starting, stopping, or changing the dosage of either drug. This record was extracted from drug labeling through openFDA. NIH/NLM RxNorm is used for drug identities. The summary and severity classification are CDI's processed information, not a verbatim source quotation. Product, route, and patient circumstances matter.
- Severity
- Major
- Carbidopa Class
- Aromatic Amino Acid Decarboxylation Inhibitor
- Carbidopa Levodopa And Entacapone Class
- Aromatic Amino Acid
- Management
- Close medical supervision required
- Data Source
- U.S. FDA via OpenFDA
Recorded Mechanism
COMT metabolism inhibition by entacapone
What To Tell Your Doctor or Pharmacist
If you are taking Carbidopa and your doctor is considering prescribing Carbidopa Levodopa And Entacapone (or vice versa), make sure to:
- Inform your doctor and pharmacist of all current medications, including over-the-counter drugs and supplements
- Ask whether the benefits of combining these medications outweigh the risks for your specific situation
- Ask what symptoms to watch for that would indicate the interaction is causing problems
- Ask how frequently you should be monitored while these are co-prescribed
- Ask whether any dosage adjustments are needed
- Never stop or change either medication without first consulting your healthcare provider