HomeMao InhibitorsMao Inhibitors + Carbidopa Levodopa And Entacapone

Does Mao Inhibitors Interact with Carbidopa Levodopa And Entacapone?

Mao Inhibitors and Carbidopa Levodopa And Entacapone have a contraindicated drug interaction according to U.S. FDA drug labeling data. Increased adrenergic tone risk. Use is contraindicated in patients receiving nonselective MAO inhibitors. The mechanism involves increased adrenergic tone. Patients taking both medications should consult their healthcare provider before starting, stopping, or changing the dosage of either drug. This information is based on official FDA drug labeling sourced from OpenFDA and the NIH National Library of Medicine.

Severity
Contraindicated
Carbidopa Levodopa And Entacapone Class
Aromatic Amino Acid
Management
Do not take together
Data Source
U.S. FDA via OpenFDA

How This Interaction Works

The interaction between Mao Inhibitors and Carbidopa Levodopa And Entacapone occurs because increased adrenergic tone. Clinically, this means increased adrenergic tone risk. use is contraindicated in patients receiving nonselective mao inhibitors. Because of the severity of this interaction, these medications are contraindicated — meaning they should not be taken together under any circumstances. If you are currently taking both, contact your healthcare provider immediately to discuss alternatives.

What To Tell Your Doctor or Pharmacist

If you are taking Mao Inhibitors and your doctor is considering prescribing Carbidopa Levodopa And Entacapone (or vice versa), make sure to:

  • Inform your doctor and pharmacist of all current medications, including over-the-counter drugs and supplements
  • Ask whether the benefits of combining these medications outweigh the risks for your specific situation
  • Ask what symptoms to watch for that would indicate the interaction is causing problems
  • Ask about alternative medications that do not interact with your current regimen
  • Ask how frequently you should be monitored while these are co-prescribed
  • Never stop or change either medication without first consulting your healthcare provider
💊 Mao Inhibitors+💊 Carbidopa Levodopa And Entacapone(Stalevo)

Severity & Interaction Details

contraindicated
Avoid this combination
FDA labeling lists this pair as contraindicated. The risk outweighs the benefit in nearly all cases.
Severity scale
MinorContra
On record
Yes
Drug A class
Drug B class
Aromatic Amino Acid
Source
NLP:carbidopa, levodopa and entacapone

What this means in plain English

Increased adrenergic tone risk. Use is contraindicated in patients receiving nonselective MAO inhibitors.

About Mao Inhibitors and Carbidopa Levodopa And Entacapone

Carbidopa Levodopa And Entacapone is an Aromatic Amino Acid. Carbidopa Levodopa And Entacapone is also sold under the brand name Stalevo. Carbidopa Levodopa And Entacapone is taken by mouth.

What the FDA label says

"Increased adrenergic tone"

📖 Source: NLP:carbidopa, levodopa and entacapone

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Data integrity: Every interaction shown is extracted directly from official U.S. FDA drug labeling via openFDA and the U.S. National Library of Medicine (NIH) — no interactions are invented, inferred, or manually edited. Maintained by CheckDrugInteractions.com. See our methodology or report a correction at support@checkdruginteractions.com.

Data sourced from U.S. FDA drug labeling via openFDA and the NIH National Library of Medicine, supplemented with a small number of well-established interactions from curated clinical references. For informational purposes only. Always consult your pharmacist or physician.