HomeChlorothiazide SodiumChlorothiazide Sodium + Chlorothiazide

Does Chlorothiazide Sodium Interact with Chlorothiazide?

Chlorothiazide Sodium and Chlorothiazide have a unknown drug interaction according to U.S. FDA drug labeling data. Refer to the package insert for lithium preparations before use of such preparations with chlorothiazide sodium. Therefore, when chlorothiazide sodium and non-steroidal anti-inflammatory agents are used concomitantly, the patient should be observed closely to determine if the desired effect of the diuretic is obtained. Patients taking both medications should consult their healthcare provider before starting, stopping, or changing the dosage of either drug. This information is based on official FDA drug labeling sourced from OpenFDA and the NIH National Library of Medicine.

Severity
Unknown
Chlorothiazide Class
Thiazide Diuretic
Management
Consult your pharmacist
Data Source
U.S. FDA via OpenFDA

What To Tell Your Doctor or Pharmacist

If you are taking Chlorothiazide Sodium and your doctor is considering prescribing Chlorothiazide (or vice versa), make sure to:

  • Inform your doctor and pharmacist of all current medications, including over-the-counter drugs and supplements
  • Ask whether the benefits of combining these medications outweigh the risks for your specific situation
  • Ask what symptoms to watch for that would indicate the interaction is causing problems
  • Never stop or change either medication without first consulting your healthcare provider
💊 Chlorothiazide Sodium(Chlorothiazide Sodium)+💊 Chlorothiazide(Diuril)

Severity & Interaction Details

ℹ️
unknown
Interaction documented — severity unclassified
The FDA label notes an interaction but the severity is not classified in our dataset.
Severity scale
MinorContra
On record
Yes
Drug A class
Drug B class
Thiazide Diuretic
Source
FDA drug label - chlorothiazide sodium

What this means in plain English

Refer to the package insert for lithium preparations before use of such preparations with chlorothiazide sodium. Therefore, when chlorothiazide sodium and non-steroidal anti-inflammatory agents are used concomitantly, the patient should be observed closely to determine if the desired effect of the diuretic is obtained.

About Chlorothiazide Sodium and Chlorothiazide

Chlorothiazide is a Thiazide Diuretic. Chlorothiazide is also sold under the brand name Diuril. Chlorothiazide Sodium is given by intravenous (IV) infusion, whereas Chlorothiazide is taken by mouth.

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Data integrity: Every interaction shown is extracted directly from official U.S. FDA drug labeling via openFDA and the U.S. National Library of Medicine (NIH) — no interactions are invented, inferred, or manually edited. Maintained by CheckDrugInteractions.com. See our methodology or report a correction at support@checkdruginteractions.com.

Data sourced from U.S. FDA drug labeling via openFDA and the NIH National Library of Medicine, supplemented with a small number of well-established interactions from curated clinical references. For informational purposes only. Always consult your pharmacist or physician.