Clonidine + Propranolol Hydrochloride Interaction
Majorinteraction on record
Description
Beta-blockers may antagonize clonidine's antihypertensive effects and rebound hypertension may result if clonidine is withdrawn abruptly. Withdraw beta-blocker several days before clonidine withdrawal.
Mechanism
Beta-blockade antagonizes clonidine's antihypertensive effects
Source: NLP:propranolol hydrochloride