Didanosine + Atazanavir Interaction

Moderateinteraction on record

Description

Coadministration with buffered formulations decreases atazanavir and didanosine concentrations. Atazanavir should be given 2 hours before or 1 hour after didanosine buffered formulations, or at different times with enteric-coated capsules.

Mechanism

pH-dependent absorption

Source: NLP:atazanavir