Does Glycopyrrolate Interact with Potassium Chloride?
CDI records a contraindicated classification for Glycopyrrolate and Potassium Chloride. The stored summary is: Solid dosage forms of potassium chloride are contraindicated due to arrested or delayed passage through GI tract with glycopyrrolate coadministration. The mechanism involves reduced gi transit time. Patients taking both medications should consult their healthcare provider before starting, stopping, or changing the dosage of either drug. This record was extracted from drug labeling through openFDA. NIH/NLM RxNorm is used for drug identities. The summary and severity classification are CDI's processed information, not a verbatim source quotation. Product, route, and patient circumstances matter.
- Severity
- Contraindicated
- Management
- Do not take together
- Data Source
- U.S. FDA via OpenFDA
Recorded Mechanism
Reduced GI transit time
What To Tell Your Doctor or Pharmacist
If you are taking Glycopyrrolate and your doctor is considering prescribing Potassium Chloride (or vice versa), make sure to:
- Inform your doctor and pharmacist of all current medications, including over-the-counter drugs and supplements
- Ask whether the benefits of combining these medications outweigh the risks for your specific situation
- Ask what symptoms to watch for that would indicate the interaction is causing problems
- Ask about alternative medications that do not interact with your current regimen
- Ask how frequently you should be monitored while these are co-prescribed
- Never stop or change either medication without first consulting your healthcare provider