Infliximab + Infliximab Axxq Interaction
Unknowninteraction on record
Description
Concomitant MTX use may decrease the incidence of anti-drug antibody production and increase infliximab product concentrations. Serum infliximab concentrations appeared to be unaffected by baseline use of medications for the treatment of CD including corticosteroids, antibiotics (metronidazole or ciprofloxacin) and aminosalicylates. Therefore, it is expected that for a molecule that antagonizes cytokine activity, such as infliximab products, the formation of CYP450 enzymes could be normalized.
Source: FDA drug label - infliximab-axxq