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Does Infliximab Axxq Interact with Metronidazole?

Infliximab Axxq and Metronidazole have a unknown drug interaction according to U.S. FDA drug labeling data. Serum infliximab concentrations appeared to be unaffected by baseline use of medications for the treatment of CD including corticosteroids, antibiotics (metronidazole or ciprofloxacin) and aminosalicylates. Patients taking both medications should consult their healthcare provider before starting, stopping, or changing the dosage of either drug. This information is based on official FDA drug labeling sourced from OpenFDA and the NIH National Library of Medicine.

Severity
Unknown
Infliximab Axxq Class
Tumor Necrosis Factor Blocker
Metronidazole Class
Nitroimidazole Antimicrobial
Management
Consult your pharmacist
Data Source
U.S. FDA via OpenFDA

What To Tell Your Doctor or Pharmacist

If you are taking Infliximab Axxq and your doctor is considering prescribing Metronidazole (or vice versa), make sure to:

  • Inform your doctor and pharmacist of all current medications, including over-the-counter drugs and supplements
  • Ask whether the benefits of combining these medications outweigh the risks for your specific situation
  • Ask what symptoms to watch for that would indicate the interaction is causing problems
  • Never stop or change either medication without first consulting your healthcare provider
💊 Infliximab Axxq(Avsola)+💊 Metronidazole(Rosadan)

Severity & Interaction Details

ℹ️
unknown
Interaction documented — severity unclassified
The FDA label notes an interaction but the severity is not classified in our dataset.
Severity scale
MinorContra
On record
Yes
Drug A class
Tumor Necrosis Factor Blocker
Drug B class
Nitroimidazole Antimicrobial
Source
FDA drug label - infliximab-axxq

What this means in plain English

Serum infliximab concentrations appeared to be unaffected by baseline use of medications for the treatment of CD including corticosteroids, antibiotics (metronidazole or ciprofloxacin) and aminosalicylates.

About Infliximab Axxq and Metronidazole

Infliximab Axxq is a Tumor Necrosis Factor Blocker, while Metronidazole is a Nitroimidazole Antimicrobial. You may recognize them by the brand names Avsola and Rosadan. Infliximab Axxq is given by intravenous (IV) infusion, whereas Metronidazole is applied to the skin. Both Infliximab Axxq and Metronidazole carry an FDA boxed warning — the agency's most serious safety designation.

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Data integrity: Every interaction shown is extracted directly from official U.S. FDA drug labeling via openFDA and the U.S. National Library of Medicine (NIH) — no interactions are invented, inferred, or manually edited. Maintained by CheckDrugInteractions.com. See our methodology or report a correction at support@checkdruginteractions.com.

Data sourced from U.S. FDA drug labeling via openFDA and the NIH National Library of Medicine, supplemented with a small number of well-established interactions from curated clinical references. For informational purposes only. Always consult your pharmacist or physician.