HomeLansoprazoleLansoprazole + Lumacaftor And Ivacaftor

Does Lansoprazole Interact with Lumacaftor And Ivacaftor?

Lansoprazole and Lumacaftor And Ivacaftor have a unknown drug interaction according to U.S. FDA drug labeling data. 7.13 Proton Pump Inhibitors, H 2 Blockers, Antacids ORKAMBI may reduce the exposure and effectiveness of proton pump inhibitors such as omeprazole, esomeprazole, and lansoprazole, and may alter the exposure of ranitidine. Patients taking both medications should consult their healthcare provider before starting, stopping, or changing the dosage of either drug. This information is based on official FDA drug labeling sourced from OpenFDA and the NIH National Library of Medicine.

Severity
Unknown
Lansoprazole Class
Proton Pump Inhibitor
Lumacaftor And Ivacaftor Class
Cystic Fibrosis Transmembrane Conductance Regulator Potentiator
Management
Consult your pharmacist
Data Source
U.S. FDA via OpenFDA

What To Tell Your Doctor or Pharmacist

If you are taking Lansoprazole and your doctor is considering prescribing Lumacaftor And Ivacaftor (or vice versa), make sure to:

  • Inform your doctor and pharmacist of all current medications, including over-the-counter drugs and supplements
  • Ask whether the benefits of combining these medications outweigh the risks for your specific situation
  • Ask what symptoms to watch for that would indicate the interaction is causing problems
  • Never stop or change either medication without first consulting your healthcare provider
💊 Lansoprazole(Prevacid)+💊 Lumacaftor And Ivacaftor(Orkambi)

Severity & Interaction Details

ℹ️
unknown
Interaction documented — severity unclassified
The FDA label notes an interaction but the severity is not classified in our dataset.
Severity scale
MinorContra
On record
Yes
Drug A class
Proton Pump Inhibitor
Drug B class
Cystic Fibrosis Transmembrane Conductance Regulator Potentiator
Source
FDA drug label - lumacaftor and ivacaftor

What this means in plain English

7.13 Proton Pump Inhibitors, H 2 Blockers, Antacids ORKAMBI may reduce the exposure and effectiveness of proton pump inhibitors such as omeprazole, esomeprazole, and lansoprazole, and may alter the exposure of ranitidine.

About Lansoprazole and Lumacaftor And Ivacaftor

Lansoprazole is a Proton Pump Inhibitor, while Lumacaftor And Ivacaftor is a Cystic Fibrosis Transmembrane Conductance Regulator Potentiator. You may recognize them by the brand names Prevacid and Orkambi. Both medications are taken by mouth.

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Data integrity: Every interaction shown is extracted directly from official U.S. FDA drug labeling via openFDA and the U.S. National Library of Medicine (NIH) — no interactions are invented, inferred, or manually edited. Maintained by CheckDrugInteractions.com. See our methodology or report a correction at support@checkdruginteractions.com.

Data sourced from U.S. FDA drug labeling via openFDA and the NIH National Library of Medicine, supplemented with a small number of well-established interactions from curated clinical references. For informational purposes only. Always consult your pharmacist or physician.