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Does Magnesium Sulfate Heptahydrate Interact with Triamterene And Hydrochlorothiazide?

CDI records a major classification for Magnesium Sulfate Heptahydrate and Triamterene And Hydrochlorothiazide. The stored summary is: Salt substitutes containing substantial amounts of potassium may promote serum potassium accumulation and hyperkalemia with triamterene. The mechanism involves potassium-sparing nature of triamterene. Patients taking both medications should consult their healthcare provider before starting, stopping, or changing the dosage of either drug. This record was extracted from drug labeling through openFDA. NIH/NLM RxNorm is used for drug identities. The summary and severity classification are CDI's processed information, not a verbatim source quotation. Product, route, and patient circumstances matter.

Severity
Major
Triamterene And Hydrochlorothiazide Class
Thiazide Diuretic
Management
Close medical supervision required
Data Source
U.S. FDA via OpenFDA

Recorded Mechanism

Potassium-sparing nature of triamterene

What To Tell Your Doctor or Pharmacist

If you are taking Magnesium Sulfate Heptahydrate and your doctor is considering prescribing Triamterene And Hydrochlorothiazide (or vice versa), make sure to:

  • Inform your doctor and pharmacist of all current medications, including over-the-counter drugs and supplements
  • Ask whether the benefits of combining these medications outweigh the risks for your specific situation
  • Ask what symptoms to watch for that would indicate the interaction is causing problems
  • Ask how frequently you should be monitored while these are co-prescribed
  • Ask whether any dosage adjustments are needed
  • Never stop or change either medication without first consulting your healthcare provider
💊 Magnesium Sulfate Heptahydrate(Magnesium Sulfate)+💊 Triamterene And Hydrochlorothiazide(Dyazide)

Severity & Interaction Details

⚠️
major
Use with caution — major interaction
Serious risk of clinically significant harm. Generally avoid; if used, monitor closely.
Severity scale
MinorContra
On record
Yes
Drug A class
—
Drug B class
Thiazide Diuretic
Source
NLP:triamterene and hydrochlorothiazide

What this means in plain English

Salt substitutes containing substantial amounts of potassium may promote serum potassium accumulation and hyperkalemia with triamterene.

About Magnesium Sulfate Heptahydrate and Triamterene And Hydrochlorothiazide

Triamterene And Hydrochlorothiazide is a Thiazide Diuretic. Triamterene And Hydrochlorothiazide is also sold under the brand name Dyazide. Triamterene And Hydrochlorothiazide additionally carries an FDA boxed warning, the FDA's strongest safety alert.

Source and Limitations

This record was produced by automated extraction from drug-label information, including AI processing. The summary and mechanism are not verbatim FDA quotations. The drug profiles below may describe different formulations from the source label. Confirm the exact product and route with your pharmacist. This page does not establish independent clinical review.

📖 Source: NLP:triamterene and hydrochlorothiazide

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How this information is prepared: CDI uses automated extraction, including AI, to summarize drug labeling from openFDA and includes separately identified curated-reference records. RxNorm helps identify medications; it does not verify interaction claims. Extracted summaries and CDI severity classifications can contain errors and are not verbatim FDA statements or independent clinical review. Maintained by CheckDrugInteractions.com. See our methodology or report a correction at support@checkdruginteractions.com.

Data sourced from U.S. FDA drug labeling via openFDA and the NIH National Library of Medicine, supplemented with a small number of well-established interactions from curated clinical references. For informational purposes only. Always consult your pharmacist or physician.

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