Mao Inhibitors + Amphetamine Extended Release Interaction
Contraindicatedinteraction on record
Description
MAOI antidepressants slow amphetamine metabolism, increasing norepinephrine release and risk of hypertensive crisis, toxic neurological effects, and potentially fatal malignant hyperpyrexia.
Mechanism
Slowed amphetamine metabolism increasing monoamine release from adrenergic nerve endings
Source: NLP:amphetamine extended-release