Mao Inhibitors + Irbesartan And Hydrochlorothiazide Interaction
Majorinteraction on record
Description
COX-2 inhibitors can reduce diuretic and antihypertensive effects, and may result in deterioration of renal function including acute renal failure. Monitor renal function and blood pressure.
Mechanism
Reduction of diuretic and natriuretic effects; renal function deterioration
Source: NLP:irbesartan and hydrochlorothiazide