Mao Inhibitors + Lisdexamfetamine Interaction
Contraindicatedinteraction on record
Description
MAOI antidepressants slow amphetamine metabolism, increasing monoamine release causing hypertensive crisis, toxic neurological effects, and potentially fatal malignant hyperpyrexia.
Mechanism
Inhibition of amphetamine metabolism leading to increased norepinephrine and monoamine release
Source: NLP:lisdexamfetamine