Mao Inhibitors + Lisdexamfetamine Dimesylate Interaction
Contraindicatedinteraction on record
Description
MAOI antidepressants slow amphetamine metabolism, increasing effects on norepinephrine release. Can cause hypertensive crisis, toxic neurological effects, and malignant hyperpyrexia with potentially fatal results.
Mechanism
MAOI slows amphetamine metabolism, increasing monoamine release from adrenergic nerve endings
Source: NLP:lisdexamfetamine dimesylate oral