Nelfinavir + Omeprazole And Sodium Bicarbonate Interaction
Majorinteraction on record
Description
Decreased exposure of some antiretroviral drugs (e.g., rilpivirine, atazanavir and nelfinavir) when used concomitantly with omeprazole may reduce antiviral effect and promote the development of drug resistance [see Clinical Pharmacology (12.3) ] . Nelfinavir: Avoid concomitant use with Omeprazole and Sodium Bicarbonate. See prescribing information for nelfinavir.
Source: FDA drug label - omeprazole, sodium bicarbonate