Nitrates + Avanafil Interaction

Contraindicatedinteraction on record

Description

Avanafil is contraindicated with organic nitrates. Avanafil potentiates the hypotensive effect of nitrates, which can be life-threatening. At least 12 hours must elapse after avanafil before nitrate administration.

Mechanism

Additive vasodilatory and hypotensive effects

Source: NLP:avanafil