Opioid Analgesics + Promethazine Hydrochloride And Dextromethorphan Hydrobromide Interaction
Majorinteraction on record
Description
Promethazine may increase, prolong, or intensify sedative action. Dose reduction recommended when given concomitantly.
Mechanism
Additive CNS depression
Source: NLP:promethazine hydrochloride and dextromethorphan hydrobromide