Oral Anticoagulants + Levothyroxine And Liothyronine Interaction
Majorinteraction on record
Description
Thyroid hormones increase catabolism of vitamin K-dependent clotting factors, impairing compensatory synthesis. Patients may require reduced anticoagulant dosage when starting thyroid replacement.
Mechanism
Increased catabolism of vitamin K-dependent clotting factors
Source: NLP:levothyroxine, liothyronine