Does Pentazocine Interact with Atropa Belladonna And Opium?
CDI records a major classification for Pentazocine and Atropa Belladonna And Opium. The stored summary is: Mixed agonist/antagonist opioid may reduce analgesic effect and/or precipitate withdrawal symptoms. Avoid concomitant use. The mechanism involves agonist/antagonist interaction. Patients taking both medications should consult their healthcare provider before starting, stopping, or changing the dosage of either drug. This record was extracted from drug labeling through openFDA. NIH/NLM RxNorm is used for drug identities. The summary and severity classification are CDI's processed information, not a verbatim source quotation. Product, route, and patient circumstances matter.
- Severity
- Major
- Management
- Close medical supervision required
- Data Source
- U.S. FDA via OpenFDA
Recorded Mechanism
Agonist/antagonist interaction
What To Tell Your Doctor or Pharmacist
If you are taking Pentazocine and your doctor is considering prescribing Atropa Belladonna And Opium (or vice versa), make sure to:
- Inform your doctor and pharmacist of all current medications, including over-the-counter drugs and supplements
- Ask whether the benefits of combining these medications outweigh the risks for your specific situation
- Ask what symptoms to watch for that would indicate the interaction is causing problems
- Ask how frequently you should be monitored while these are co-prescribed
- Ask whether any dosage adjustments are needed
- Never stop or change either medication without first consulting your healthcare provider