Reserpine + Tetrabenazine Interaction
Contraindicatedinteraction on record
Description
Should not be used concomitantly. Must wait at least 20 days after stopping reserpine before starting tetrabenazine to avoid overdosage and major CNS depletion of serotonin and norepinephrine.
Mechanism
Both deplete monoamines via VMAT2 binding
Source: NLP:tetrabenazine