Does Sodium Polystyrene Sulfonate Interact with Aluminum Carbonate?
CDI records a major classification for Sodium Polystyrene Sulfonate and Aluminum Carbonate. The stored summary is: Concomitant use with sodium polystyrene sulfonate may cause systemic alkalosis and reduce potassium exchange capability. The mechanism involves cation exchange interaction with nonabsorbable cation-donating antacid. Patients taking both medications should consult their healthcare provider before starting, stopping, or changing the dosage of either drug. This record was extracted from drug labeling through openFDA. NIH/NLM RxNorm is used for drug identities. The summary and severity classification are CDI's processed information, not a verbatim source quotation. Product, route, and patient circumstances matter.
- Severity
- Major
- Sodium Polystyrene Sulfonate Class
- Potassium Binder
- Management
- Close medical supervision required
- Data Source
- U.S. FDA via OpenFDA
Recorded Mechanism
Cation exchange interaction with nonabsorbable cation-donating antacid
What To Tell Your Doctor or Pharmacist
If you are taking Sodium Polystyrene Sulfonate and your doctor is considering prescribing Aluminum Carbonate (or vice versa), make sure to:
- Inform your doctor and pharmacist of all current medications, including over-the-counter drugs and supplements
- Ask whether the benefits of combining these medications outweigh the risks for your specific situation
- Ask what symptoms to watch for that would indicate the interaction is causing problems
- Ask how frequently you should be monitored while these are co-prescribed
- Ask whether any dosage adjustments are needed
- Never stop or change either medication without first consulting your healthcare provider