Does Sucroferric Oxyhydroxide Interact with Acetylsalicylic Acid?
Sucroferric Oxyhydroxide and Acetylsalicylic Acid have a moderate drug interaction according to U.S. FDA drug labeling data. Acetylsalicylic acid should be taken at least 1 hour before sucroferric oxyhydroxide to avoid reduced bioavailability. The mechanism involves binding interaction reducing bioavailability. Patients taking both medications should consult their healthcare provider before starting, stopping, or changing the dosage of either drug. This information is based on official FDA drug labeling sourced from OpenFDA and the NIH National Library of Medicine.
- Severity
- Moderate
- Sucroferric Oxyhydroxide Class
- Phosphate Binder
- Management
- Monitor for effects
- Data Source
- U.S. FDA via OpenFDA
How This Interaction Works
The interaction between Sucroferric Oxyhydroxide and Acetylsalicylic Acid occurs because binding interaction reducing bioavailability. Clinically, this means acetylsalicylic acid should be taken at least 1 hour before sucroferric oxyhydroxide to avoid reduced bioavailability. This is classified as a moderate interaction. While it may not require stopping either medication, your healthcare provider should be aware you are taking both so they can monitor for potential effects and adjust treatment if necessary.
What To Tell Your Doctor or Pharmacist
If you are taking Sucroferric Oxyhydroxide and your doctor is considering prescribing Acetylsalicylic Acid (or vice versa), make sure to:
- Inform your doctor and pharmacist of all current medications, including over-the-counter drugs and supplements
- Ask whether the benefits of combining these medications outweigh the risks for your specific situation
- Ask what symptoms to watch for that would indicate the interaction is causing problems
- Ask whether any dosage adjustments are needed
- Never stop or change either medication without first consulting your healthcare provider