Terbinafine Tablets 250 Mg + Fluconazole Interaction

Unknowninteraction on record

Description

Drug interactions have also been noted with cimetidine, fluconazole, cyclosporine, rifampin, and caffeine. The influence of terbinafine on the pharmacokinetics of fluconazole, cotrimoxazole (trimethoprim and sulfamethoxazole), zidovudine or theophylline was not considered to be clinically significant. Coadministration of a single dose of fluconazole (100 mg) with a single dose of terbinafine resulted in a 52% and 69% increase in terbinafine C max and AUC, respectively.

Source: FDA drug label - terbinafine tablets 250 mg