Amitriptyline + Levothyroxine Sodium Anhydrous Interaction
Majorinteraction on record
Description
Concurrent use may increase therapeutic and toxic effects of both drugs, including increased risk of cardiac arrhythmias and CNS stimulation, with accelerated onset of tricyclic action.
Mechanism
Increased receptor sensitivity to catecholamines
Source: NLP:levothyroxine sodium anhydrous