Does Delafloxacin Meglumine Interact with Didanosine?
CDI records a moderate classification for Delafloxacin Meglumine and Didanosine. The stored summary is: Didanosine formulations containing divalent and trivalent cations form chelates with delafloxacin, substantially interfering with absorption and resulting in considerably lower systemic concentrations. The mechanism involves chelation with divalent and trivalent cations. Patients taking both medications should consult their healthcare provider before starting, stopping, or changing the dosage of either drug. This record was extracted from drug labeling through openFDA. NIH/NLM RxNorm is used for drug identities. The summary and severity classification are CDI's processed information, not a verbatim source quotation. Product, route, and patient circumstances matter.
- Severity
- Moderate
- Management
- Monitor for effects
- Data Source
- U.S. FDA via OpenFDA
Recorded Mechanism
Chelation with divalent and trivalent cations
What To Tell Your Doctor or Pharmacist
If you are taking Delafloxacin Meglumine and your doctor is considering prescribing Didanosine (or vice versa), make sure to:
- Inform your doctor and pharmacist of all current medications, including over-the-counter drugs and supplements
- Ask whether the benefits of combining these medications outweigh the risks for your specific situation
- Ask what symptoms to watch for that would indicate the interaction is causing problems
- Ask whether any dosage adjustments are needed
- Never stop or change either medication without first consulting your healthcare provider