Glipizide And Metformin Hydrochloride + Fluconazole Interaction
Unknowninteraction on record
Description
The effect of concomitant administration of fluconazole and glipizide has been demonstrated in a placebo-controlled crossover study in normal volunteers. All subjects received glipizide alone and following treatment with 100 mg of fluconazole as a single oral daily dose for 7 days, the mean percent increase in the glipizide AUC after fluconazole administration was 56.9% (range: 35% to 81%).
Source: FDA drug label - glipizide and metformin hydrochloride