Does Lumacaftor And Ivacaftor Interact with Methylprednisolone?
Lumacaftor And Ivacaftor and Methylprednisolone have a unknown drug interaction according to U.S. FDA drug labeling data. Concomitant use of ORKAMBI may reduce the exposure and effectiveness of prednisone and methylprednisolone. Patients taking both medications should consult their healthcare provider before starting, stopping, or changing the dosage of either drug. This information is based on official FDA drug labeling sourced from OpenFDA and the NIH National Library of Medicine.
- Severity
- Unknown
- Lumacaftor And Ivacaftor Class
- Cystic Fibrosis Transmembrane Conductance Regulator Potentiator
- Methylprednisolone Class
- Corticosteroid
- Management
- Consult your pharmacist
- Data Source
- U.S. FDA via OpenFDA
What To Tell Your Doctor or Pharmacist
If you are taking Lumacaftor And Ivacaftor and your doctor is considering prescribing Methylprednisolone (or vice versa), make sure to:
- Inform your doctor and pharmacist of all current medications, including over-the-counter drugs and supplements
- Ask whether the benefits of combining these medications outweigh the risks for your specific situation
- Ask what symptoms to watch for that would indicate the interaction is causing problems
- Never stop or change either medication without first consulting your healthcare provider