Mao Inhibitors + Amphetamine Sulfate Interaction

Contraindicatedinteraction on record

Description

MAOIs slow amphetamine metabolism, potentiating effects and risk of hypertensive crisis, neurological toxicity, and potentially fatal malignant hyperpyrexia.

Mechanism

Inhibition of amphetamine metabolism increases norepinephrine and monoamine release

Source: NLP:amphetamine sulfate