Mao Inhibitors + Olmesartan Medoxomil Hydrochlorothiazide Interaction
Majorinteraction on record
Description
Dual blockade of the RAS is associated with increased risks of hypotension, hyperkalemia, and changes in renal function including acute renal failure. Avoid combined use.
Mechanism
Dual RAS inhibition leads to excessive suppression of the renin-angiotensin system
Source: NLP:olmesartan medoxomil-hydrochlorothiazide